The Alzheimer's Solution

The Alzheimer's Solution

A Breakthrough Program to Prevent and Reverse the Symptoms of Cognitive Decline at Every Age

Book - 2017
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"A revolutionary, proven program for reversing the symptoms of Alzheimer's disease and cognitive decline from award winning neurologists and codirectors of the Brain Health and Alzheimer's Prevention Program at Loma Linda University Medical Center"-- Provided by publisher.
The Sherzais believe that 90 percent of Alzheimer's cases can be prevented. Based on their clinical studies, they have devised a comprehensive program for preventing Alzheimer's disease and improving cognitive function. The brain is a living universe, directly influenced by nutrition, exercise, stress, sleep, and engagement. These factors are the pillars of a program that evaluates risk, offers suggestions for prevention and symptom-reversal, and provides day-by-day guides for optimizing cognitive function. The future of your brain is finally within your control.
Publisher: New York, NY : HarperOne, [2017]
Edition: First edition
ISBN: 9780062666475
Branch Call Number: 616.8311 SHERZAI 2017
Characteristics: 352 pages : illustrations ; 24 cm
Additional Contributors: Sherzai, Ayesha - Author


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Oct 17, 2018

This is THE BEST of all the books about how to reverse Alzheimers.
Although Bredesen's book gets a lot more press because he also published his results in the scientific journals, When I talk to people who are following Bredesen's protocal, it is obvious that they are MISUNDERSTANDING some of what he recommends -- and it's easy to see why after reading his book. He actually contradicts himself in terms of how much animal protein is optimal, and people looking for good news about their bad habits -- prefer his protocal because of this.
However when I saw Bredesen and his SUCCESSFUL patients interviewed on a talk show -- it became very clear that they were actually following a plant-based diet for the most part.
That is why THIS book is the best -- reading it won't confuse you about what is optimal and will best enable you to actually get good results.
Two reviews below this one, I noticed someone criticized this book and Ansel Keys -- so I want to respond to that. They obviously have been influenced by the Cholesterol Deniers -- folks who fell prey to big ag interests using the big tobacco play book. Anytime you see someone dissing Keys -- you should immediately be suspicious that this is the case. Keys work was impeccable -- but has come under fire by sophisticated attacks seeking to discredit him and if you aren't educated in the real facts, you too may be misled.
Read more about Keys here:

Apr 25, 2018

Association of Radon Background and Total Background Ionizing Radiation with Alzheimer’s
Disease Deaths in U.S. States

Published in The Journal of Alzheimer's Disease (, vol. 59, no. 2, pp. 737-741, 2017

Results: Radon background ionizing radiation was significantly correlated with AD death rate in 50 states and the District of Columbia (r = 0.467, p = 0.001).

Using a mechanical ventilation system to provide fresh filtered air can:
1. Dilute, and flush-out, odors, chemicals, CO2, microbes, and radon.
2. Prevent exposure to chemicals and CO2 at elevated levels that can significantly decrease cognitive functions. Reference:
3. Make it safe to seal the many air leaks in building envelopes to block entry of dust, drafts and insects.

Nov 26, 2017

The Alzheimer’s solution: Excellent on numerous counts with a couple of caveats. The authors, two qualified neurologists, have developed an empirical and scientific based approach to reducing and preventing the symptoms of Alzheimer’s disease. I read this book fairly shortly after reading the equally excellent “The End of Alzheimer’s” by Dale Bredesen. As can be expected both respective authors/books approach to managing and reducing the risk of Alzheimer’s Disease (AD) overlap a lot. Their approaches are based on healthy lifestyle modifications.
While Bredesen is mainly focused on nutrition and fasting, the Sherzais have a more multidimensional approach including also exercise, meditation, sleep, and building cognitive reserves (exercising your brain).
The Sherzais are also really strong in explaining the different causal mechanisms that cause AD including: 1) oxidation; 2) inflammation; 3) glucose dysregulation; and 4) lipid dysregulation. By contrast, Bredesen is mainly focused on inflammation. He also mentioned inadequate nutritional and hormonal support to the brain as a second factor and toxicity (mercury, etc.) as a third factor. However, on this count I do find the Sherzais explanation of AD much more thorough from a physiological standpoint.
There is one chapter where one has to express reservation, and it is the one on nutrition. They stick to a low fat, low cholesterol mantra relying on the research by Ancel Keys dating back to 1951. We now know his research was highly biased, and his conclusion very much wrong. Extensive scientific rebuttals have been disclosed in numerous books. Probably the best one on the subject is Uffe Ravnskov’s “The Cholesterol Myth” published in 1999. But, other current books also hammer away on the fallacies of Keys’ studies, including Dr. Mercola’s “Fat for Fuel” among many others. In view of the Sherzais diverging views on nutrition, they constantly warn against the profound ill impact of saturated fats and eggs (cholesterol). Well, in both cases they are deemed inaccurate by many other neurologists and nutritionist experts much concerned about overall health and the health of the brain. In this camp you will find not only Ravnskov and Mercola, but also Dale Bredesen, and Steven Gundry (the author of “The Plant Paradox”).
Saturated fats are associated with numerous health benefits including enhancing absorption of numerous vitamins and minerals, boosting HDL levels (the good cholesterol), enhancing mitochondria energy metabolism, contributing to brain health (the brain does need much fat to function).
Another area where the Sherzais impart questionable information is concerning the overall risk of AD. On page 22, they indicate that if you have no ApoE4 genes, you have a 50% risk of developing AD by 85 years old. 23andme, a genetic testing company, relying on a very large sample of Caucasians, discloses an AD risk that is more than 5 x lower than the Sherzais. They come up with a risk of 5-8% for men and 6-10% for women. The Framingham Study comes up with an overall risk of AD (that does not exclude individuals that have the ApoE4 genes) by 85 years old of 12% for men and 20% for women.

Oct 12, 2017

With support in lifestyle research and personalized medicine, the authors report from their work at the Brain Health center at Loma Linda University Medical Center on a plan for reducing the risk, and sometimes even reversing the early symptoms of, cognitive decline. The plan involves personalized approaches to healthy living for people of all ages, with benefits even from small and incremental changes: Nutrition in a healthy and whole-food diet, Exercise spread throughout the day where possible, Unwinding from stress through relaxation and social support, Restorative sleep, and Optimizing brain function by engaging it in activities such as music and learning languages, and in meaningful social interaction. Helpful supplements to the text include personalized questionnaires, diet, meditation and exercise guides, and even a set of brain-friendly recipes.


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